Publications

2007

• A lipidomic analysis of nonalcoholic fatty liver disease.
  Puri P, Baillie RA, Wiest MM, Mirshahi F, Choudhury J, Cheung O, Sargeant C, Contos MJ, Sanyal AJ.
  Hepatology. 2007 Oct;46(4):1081-90.
  
• Functional annotation of genomic data with metabolic inference.
  Walzem RL, Baillie RA, Wiest M, Davis R, Watkins SM, Porter TE, Simon J, Cogburn LA.
  Poult Sci. 2007 Jul;86(7):1510-22.
  
• Biomarker discovery using high-dimensional lipid analysis.
  Wiest MM, Watkins SM.
  Curr Opin Lipidol. 2007 Apr;18(2):181-6.
• Lipidomics and lipid profiling in metabolomics.
  German JB, Gillies LA, Smilowitz JT, Zivkovic AM, Watkins SM.
  Curr Opin Lipidol. 2007 Feb;18(1):66-71.
  

2006

• Increased oxidative stress is associated with balanced increases in hepatocyte apoptosis and proliferation in glycerol-3-phosphate acyltransferase-1 deficient mice.
  Hammond LE, Albright CD, He L, Rusyn I, Watkins SM, Doughman SD, Lemasters JJ, Coleman RA.
  Exp Mol Pathol. 2006 Dec 28.
• Agpat6--a novel lipid biosynthetic gene required for triacylglycerol production in mammary epithelium.
  Beigneux AP, Vergnes L, Qiao X, Quatela S, Davis R, Watkins SM, Coleman RA, Walzem RL, Philips M, Reue K, Young SG.
  Journal of Lipid Research. 2006 Apr; 47(4):734-44.
• Agpat6 deficiency causes subdermal lipodystrophy and resistance to obesity.
  Vergnes L, Beigneux AP, Davis R, Watkins SM, Young SG, Reue K.
  Journal of Lipid Research. 2006 Apr; 47(4): 745-54.
• Targeted Deletion of FATP5 Reveals Multiple Functions in Liver Metabolism: Alterations in Hepatic Lipid Homeostasis.
  Doege H, Baillie RA, Ortegon AM, Tsang B, Wu Q, Punreddy S, Hirsch D, Watson N, Gimeno RE, Stahl A.
  Gastroenterology. 2006 Feb.

2005

• Metabolomics in Practice: Emerging Knowledge to Guide Future Dietetic Advice toward Individualized Health
  German JB, Watkins SM, Fay LB.
  Journal of the American Dietetic Association. 2005 Sep; 105(9):1425-32.
• Focused metabolomic profiling in the drug development process: advances from lipid profiling.
  Morris M, Watkins SM.
  Current opinion in chemical biology. 2005 Aug; 9(4):407-12
• Metabolomics: Building on a century of biochemistry to guide human health.
  German JB, Hammock BD, Watkins SM.
  Metabolomics, 2005 Mar; 1(2):3-9.
• An integrative metabolism approach identifies stearoyl-CoA desaturase as a target for an arachidonate-enriched diet.
  Mutch DM, Grigorov M, Berger A, Fay LB, Roberts MA, Watkins SM, Williamson G, German JB.
  FASEB J. 2005 Apr; 19(6):599-601. Epub 2005 Jan 24.

2004

• Metabolic assessment—a key to nutritional strategies for health.
  J.B. German and S.M. Watkins
  Trends in Food Science & Technology, 2004 Nov; 15(11), Pages 541-549
• Lipopenia and skin barrier abnormalities in DGAT2-deficient mice.
  Stone SJ, Myers HM, Watkins SM, Brown BE, Feingold KR, Elias PM, Farese RV Jr.
  Journal of Biological Chemistry 2004 Mar 19; 279(12):11767-76.
• Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on fatty acid availability and neural tube formation in cynomolgus macaque, Macaca fascicularis.
  Moran FM, Hendrickx AG, Shideler S, Overstreet JW, Watkins SM, Lasley BL.
  Birth Defects Res Part B Dev Reprod Toxicol. 2004 Feb; 71(1):37-46.
• Lipomic profiling in drug discovery, development and clinical trial evaluation.
  Watkins SM.
  Current Opinion in Drug Discovery and Development, 2004 Jan; 7(1):112-117.

External Publications

• Synthetic LXR agonists increase LDL in CETP species.
  Groot PH, Pearce NJ, Yates JW, Stocker C, Sauermelch C, Doe CP, Willette RN, Olzinski A, Peters T, d'Epagnier D, Morasco KO, Krawiec JA, Webb CL, Aravindhan K, Jucker B, Burgert M, Ma C, Marino JP, Collins JL, Macphee CH, Thompson SK, Jaye M.
  Journal of Lipid Research. 2005 Oct; 46(10):2182-91.
• The Fatty Acid-binding Protein, aP2, Coordinates Macrophage Cholesterol Trafficking and Inflammatory Activity.
  Liza Makowski, Katherine C. Brittingham, Joseph M. Reynolds, Jill Suttles,and Gökhan S. Hotamisligil.
  Journal of Biological Chemistry, 2005 Apr 1; 280(13):12888-95.
• Dexamethasone treatment in the newborn rat: fatty acid profiling of lung, brain, and serum lipids.
  Bruder ED, Lee PC, Raff H.
  J Appl Physiol. 2005 Mar; 98(3):981-90.
• Lipid and fatty acid profiles in the brain, liver, and stomach contents of neonatal rats: effects of hypoxia.
  Bruder ED, Lee PC, Raff H.
  Am J Physiol Endocrinol Metab. 2005 Feb; 288(2):E314-20.
• Metabolic consequences of hypoxia from birth and dexamethasone treatment in the neonatal rat: comprehensive hepatic lipid and fatty acid profiling.
  Bruder ED, Lee PC, Raff H.
  Endocrinology. 2004 Nov;145(11):5364-72.
• Metabolomic analysis of adrenal lipids during hypoxia in the neonatal rat: implications in steroidogenesis.
  Bruder ED, Lee PC, Raff H.
  Am J Physiol Endocrinol Metab. 2004 May; 286(5):E697-703.
• The Drosophila microRNA Mir-14 suppresses cell death and is required for normal fat metabolism.
  Xu P, Vernooy SY, Guo M, Hay BA.
  Curr Biol. 2003 Apr 29;13(9):790-5.