Metabolomics Connects the Genome to Phenotype


WEBINAR: Metabolomics Connects the Genome to Phenotype

Metabolon invites you to join us for a free, 60-minute webinar, Metabolomics Connects the Genome to Phenotype.

Monday, April 10, 2017
11am EDT

Presenter: John Ryals, Ph.D., President and CEO, Metabolon

Understanding phenotypes is the central need for enabling research and medical advances. The exploration of gene function and the use of genomics tools have been a focal-point for unraveling phenotypes for the last two decades. But, while these genomic tools have provided many important insights and discoveries, a staggeringly complex picture has also emerged. Deciphering the meaningful biological signal from noise amongst all of this complexity is a persistent challenge.

Since metabolites are regarded as an intermediate phenotype, metabolomics has emerged as an ideal way to bridge the genotype-phenotype relationship. However, there are critical considerations to successful implementation of metabolomics; platforms must be highly stable, scalable and able to capture a meaningfully broad swath of the metabolites within a biological sample.

In this first of a 4-part series, we will review the history of phenotyping with genomic approaches and outline some of the key challenges and how metabolomics has become an important companion.

We will also detail some of the key technological hurdles that had to be overcome so that metabolomics could contribute to defining phenotypes, as well as gene activity and function. Finally, to kick-off the webinar series, we will briefly summarize how metabolomics is contributing to human genetics, transcriptional profiling and microbiome research.

To register, please click here.